A group of researchers at Tehran Medical Sciences University have designed and built a well-structured scaffolding to reconstruct bone defects.

The scaffolding made with nano-hydroxyapatite-gelatin can be used in parts of bone removed due to reasons such as cancer and infection. In terms of mechanical properties, the newly-developed system is similar to the spongy bone tissue and has showed good level of biocompatibility.

It can also be designed at the defect areas suffering different forms of fracture or trauma because it is made in layer form.

The achievement can be used in cases, where part of the bone has been removed due to osteotomy because of different reasons such as cancer and infection, if the bone is not undergoing pressure.

In case the scaffolding is analyzed, it would be turned into calcium, phosphor and gelatin which can be used for body or be disposed without any damage to the body.

The structure of the scaffolding, optimized size of the cavity, its mechanical properties and layer-formed model help it to be designed in the form of the defect's place.

The results of the study have been published in the ‏Journal of nanoparticle research.

HK