Iranian researchers regenerate kidney using stem cells

Dr. Reza Moghaddasali told Mehr News that they selected cellular therapy of acute and chronic diseases in animal media with good results. He also expressed hope that a day would come when the results of the study would be used for human kidney disorders.

He cited hypertension and diabetes as factors of kidney disorders. “The most common treatment is transplant, which according to global data, 20 per cent of patients develop inflammatory reaction to the transplanted organ. Thus, we have in the agenda to regenerated the failing tissues of kidney,” the project manager said.

“We regenerated failed kidney tissues in monkeys using Cisplatin chemotherapeutic drug, and then we injected stem cells to failed tissues, which improved their function,” he added.

Moghaddasali cited decreased Natrium and urea as symptomatic of improved kidney function in animal media. “We are planning to use these cells in human media,” he said, pointing to other Royan Institute other research projects. “In engineering of kidney tissues, we are working to develop a connective tissue using kidney tissues,” he added, expressing hope that in coming years he would use these findings clinically.

HK