The victims were taken to Kuwaiti and Mohammed Yousef El-Najar hospitals in Rafah.
The first strike targeted a house belonging to the Al-Khatib family in the Jneina neighborhood, resulting in three fatalities, including a child, and several injuries.
The second airstrike targeted a house belonging to the Al-Khawaja family in the Shabora refugee camp, resulting in the deaths of seven Palestinians, including a baby, and injuring others.
Ten Palestinians, including three children, were also killed, and several others injured in a third airstrike targeting a house belonging to the Abu Taha family in the Salam neighborhood.
Israel has stepped up airstrikes on Rafah, where it has vowed to launch an all-out assault despite international outcry as it could cause mass casualties. The southern city hosts more than a million people displaced from the war in Gaza.
Israel has pounded the Gaza Strip since a cross-border attack by Hamas on Oct. 7, 2023 which killed some 1,200 people.
Besides killing more than 34,000 Palestinians since then, the military campaign has turned much of the enclave of 2.3 million people into ruins, leaving most civilians homeless and at risk of famine.